SCHEMBL865527

SCHEMBL865527

C=CC(=O)OC([O])CCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.44
HPGD P15428 1/20 0.44
THRB P10828 4/20 0.38
ALDH1A1 P00352 5/20 0.35
CYP3A4 P08684 4/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.34
CTSK P43235 2/20 0.34
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20913255 0.88 TSHR (0.53) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL7234032 0.86 TSHR (0.48) TSHRHPGDTHRBTHRA
SCHEMBL865625 0.85 TSHR (0.47) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL7236277 0.85 TSHR (0.47) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL865080 0.83
SCHEMBL8970460 0.82 TSHR (0.46) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL544590 0.81 TSHR (0.45) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL9545994 0.81 TSHR (0.45) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL28549177 0.79 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL26503 0.79 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2390684-B1 OPTICAL ELEMENT COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT CANON KK (JP) 2019-04-24 EP claimed
EP-0263022-A1 Mesomorphic polymers containing side chains, derived from 1-(phenyl)-2-(4-cyanophenyl) ethane THOMSON-CSF (FR) 1988-04-06 EP claimed
EP-0241338-A1 Mesomorphous polymers with highly dielectrical anisotropie lateral chains, and process for their preparation THOMSON-CSF (FR) 1987-10-14 EP claimed
WO-2024143339-A1 OPTICAL ANISOTROPIC LAYER, LIGHT GUIDE ELEMENT, AND AR DISPLAY DEVICE 富士フイルム株式会社 2024-07-04 WO disclosed
WO-2024143347-A1 OPTICAL ANISOTROPIC LAYER, LAMINATE, LIGHT GUIDE ELEMENT, AND AR DISPLAY DEVICE 富士フイルム株式会社 2024-07-04 WO disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
US-11977290-B2 Liquid crystal diffraction element, optical element, image display unit, head-mounted display, beam steering, and sensor FUJIFILM CORPORATION (JP) 2024-05-07 US disclosed
US-20240045335-A1 EXPOSURE METHOD OF PHOTOALIGNMENT LAYER FUJIFILM CORPORATION (JP) 2024-02-08 US disclosed
US-20240045334-A1 EXPOSURE METHOD OF PHOTOALIGNMENT LAYER FUJIFILM CORPORATION (JP) 2024-02-08 US disclosed
US-20240036343-A1 LIQUID CRYSTAL DIFFRACTION ELEMENT, IMAGE DISPLAY APPARATUS, AND HEAD MOUNTED DISPLAY FUJIFILM CORPORATION (JP) 2024-02-01 US disclosed
US-20230244012-A1 TRANSMISSIVE LIQUID CRYSTAL DIFFRACTION ELEMENT FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 EP disclosed
EP-1860094-A1 Photocrosslinkable materials Rolic AG (CH) 2007-11-28 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed
US-6589445-B2 Irradiating; changing twisting structure FUJI PHOTO FILM CO., LTD. (JP) 2003-07-08 US disclosed
US-20020033479-A1 Light-reaction type optically active compound, light-reaction type chiral agent, liquid crystal composition, liquid crystal color filter, optical film, recording medium, and method of changing twist structure of liquid crystal FUJI PHOTO FILM CO., LTD. 2002-03-21 US disclosed
EP-0263022-A1 Mesomorphic polymers containing side chains, derived from 1-(phenyl)-2-(4-cyanophenyl) ethane THOMSON-CSF (FR) 1988-04-06 EP disclosed
EP-0241338-A1 Mesomorphous polymers with highly dielectrical anisotropie lateral chains, and process for their preparation THOMSON-CSF (FR) 1987-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD TSHR 3933/4885HPGD 852/4885THRB 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.