SCHEMBL28219948

SCHEMBL28219948

CCCC(C)S(=O)(=O)NCC[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 3/20 0.35
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28220005 0.78 GRIA1 (0.58) GRIA1
SCHEMBL24401280 0.74 ALDH1A1 (0.47) GRIA1CA1
SCHEMBL24303319 0.73 GRIA1 (0.42) GRIA1CA1
SCHEMBL9612083 0.69 TP53 (0.35) GRIA1CA1
SCHEMBL28219980 0.69 MEN1 (0.37) CA1
SCHEMBL12425770 0.67 CA1 (0.50) GRIA1CA1
SCHEMBL28219991 0.66 POLB (0.36) CA1
SCHEMBL11707456 0.66 HDAC7 (0.33)
SCHEMBL17630066 0.65 CA1 (0.34) GRIA1CA1
SCHEMBL12384310 0.64 GRIA1 (0.40) GRIA1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137545-A TRIAZOLE AGONISTS OF THE APJ RECEPTOR 美国安进公司 2018-06-08 CN disclosed