Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583086 | 1.00 | MAOA (0.54) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL5745844 | 0.78 | MAOA (0.50) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL16506046 | 0.78 | KDM4E (0.47) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL5706967 | 0.78 | KDM4E (0.47) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL6822558 | 0.78 | MAOA (0.50) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL11734493 | 0.78 | KDM4E (0.52) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL437696 | 0.78 | KDM4E (0.50) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL11295043 | 0.78 | ERN1 (0.55) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL201997 | 0.78 | MAOA (0.50) | MAOAMAOBKDM4EGPR3PDE4A | |
| SCHEMBL601463 | 0.78 | MAOA (0.50) | MAOAMAOBKDM4EGPR3PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751137-A | Method for preparing chloro aromatic compound by photo-induced nitroarene denitration chlorination | 华中师范大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-113057167-A | Herbicide composition containing quinclorac and sulfentrazone and applied to paddy field | 山东省农业科学院植物保护研究所 | 2021-07-02 | — | — | CN | disclosed |
| CN-109715612-A | SOMATOSTATIN MODULATORS AND USES THEREOF | 克林提克斯医药股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-108137547-A | It can be used as the heterocyclic compound of TNF α conditioning agent | 百时美施贵宝公司 | 2018-06-08 | — | — | CN | disclosed |