Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 13/20 | 0.85 |
| ▸ | EPAS1 | Q99814 | 13/20 | 0.85 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28220149 | 1.00 | HIF1A (0.85) | HIF1AEPAS1GPR84FAAHTRPV1 | |
| SCHEMBL28220715 | 1.00 | HIF1A (0.85) | HIF1AEPAS1GPR84FAAHTRPV1 | |
| SCHEMBL28220717 | 1.00 | HIF1A (0.85) | HIF1AEPAS1GPR84FAAHTRPV1 | |
| SCHEMBL3204504 | 0.97 | HIF1A (0.89) | HIF1AEPAS1GPR84FAAHTRPV1 | |
| SCHEMBL9385000 | 0.92 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL7778346 | 0.92 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL22342730 | 0.92 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| Mycalazal 14 SCHEMBL28220153 | 0.92 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL28220708 | 0.92 | HIF1A (1.00) | HIF1AEPAS1GPR84 | |
| SCHEMBL28220705 | 0.92 | HIF1A (1.00) | HIF1AEPAS1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003083-A | The method and its pyrroles's aldehyde compound of pyrroles's aldehyde compound are separated in a kind of mountain and sea silk floss from blade | 厦门医学院 | 2018-05-08 | — | — | CN | disclosed |