Butanol

Butanol

SCHEMBL28220171

CC(=O)CC(C)=O.CCC(C)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.59
ALDH1A1 P00352 5/20 0.42
TDP1 Q9NUW8 3/20 0.42
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
HTT P42858 1/20 0.36
USP2 O75604 1/20 0.35
KDM4E B2RXH2 1/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
TP53 P04637 1/20 0.33
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL29001537 0.87 TSHR (0.50) TSHRALDH1A1TDP1MGAMGAA
Acetoacetic Acid SCHEMBL1493223 0.87 TSHR (0.50) TSHRALDH1A1TDP1MGAMGAA
Butanone SCHEMBL1576889 0.85 TDP1 (0.62) TSHRALDH1A1TDP1TP53TRPA1
Butanol SCHEMBL25345835 0.84
Isopropyl Alcohol SCHEMBL28237623 0.84 ALDH1A1 (0.47) TSHRALDH1A1TDP1MGAMGAA
Isopropyl Alcohol SCHEMBL8457735 0.84 ALDH1A1 (0.47) TSHRALDH1A1TDP1MGAMGAA
Butanol SCHEMBL5317804 0.84 TSHR (0.71) TSHRALDH1A1TDP1TP53
Acetoacetic Acid SCHEMBL31448154 0.83 TSHR (0.46) TSHRALDH1A1TDP1
Propylene Glycol SCHEMBL28916411 0.82 TDP1 (0.59) TSHRALDH1A1TDP1MGAMGAA
Butanol SCHEMBL1028571 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105618063-B It is a kind of for beta-diketon Hydrogenation for beta-diol catalyst 中国石油化工股份有限公司 2018-08-17 CN disclosed
CN-105566068-B A kind of method for beta-diketon Hydrogenation for beta-diol 中国石油化工股份有限公司 2018-05-11 CN disclosed