Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142027 | 0.73 | TSHR (0.42) | SMN1; SMN2TSHRHTTPOLBHSD17B10 | |
| SCHEMBL424451 | 0.73 | TSHR (0.39) | SMN1; SMN2TSHRPOLBMAPTL3MBTL1 | |
| SCHEMBL6396268 | 0.72 | POLB (0.43) | SMN1; SMN2TSHRHTTPOLBHSD17B10 | |
| SCHEMBL4744925 | 0.71 | POLB (0.42) | SMN1; SMN2TSHRHTTPOLBHSD17B10 | |
| SCHEMBL8939927 | 0.69 | HTT (0.38) | SMN1; SMN2TSHRHTTPOLBHSD17B10 | |
| SCHEMBL5114693 | 0.68 | TSHR (0.37) | SMN1; SMN2TSHRHTTPOLBHSD17B10 | |
| SCHEMBL27607927 | 0.67 | POLB (0.39) | SMN1; SMN2TSHRHTTPOLBHSD17B10 | |
| SCHEMBL28189069 | 0.67 | TSHR (0.40) | SMN1; SMN2TSHRHTTPOLBKDM4E | |
| SCHEMBL28005178 | 0.66 | POLB (0.38) | SMN1; SMN2TSHRHTTPOLBMAPT | |
| SCHEMBL7015140 | 0.65 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRHTTPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108125961-A | Morpholinyl acetylamino anisyl benzo-aza * bases quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |