Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939927 | 0.85 | HTT (0.38) | POLBHTTTSHRHSD17B10ALDH1A1 | |
| SCHEMBL4744925 | 0.82 | POLB (0.42) | POLBHTTTSHRHSD17B10ALDH1A1 | |
| SCHEMBL28023530 | 0.81 | L3MBTL1 (0.32) | KMT2AL3MBTL1 | |
| SCHEMBL5142027 | 0.81 | TSHR (0.42) | POLBHTTTSHRHSD17B10ALDH1A1 | |
| SCHEMBL27858121 | 0.79 | L3MBTL1 (0.34) | POLBHTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27607927 | 0.78 | POLB (0.39) | POLBHTTTSHRHSD17B10ALDH1A1 | |
| SCHEMBL6632262 | 0.76 | SIGMAR1 (0.36) | KMT2A | |
| SCHEMBL2920413 | 0.76 | HSD17B10 (0.36) | POLBTSHRHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL18505994 | 0.75 | SMN1; SMN2 (0.47) | POLBHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4754126 | 0.74 | POLB (0.37) | POLBHTTTSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |