Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 6/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068077 | 0.84 | PPARD (0.68) | PPARDPPARGPPARA | |
| SCHEMBL2820978 | 0.83 | GRM5 (0.44) | GRM5ERN1NPC1HCRTR1RAB9A | |
| SCHEMBL2822183 | 0.81 | PPARD (0.44) | PPARDPPARGPPARAGRM5 | |
| SCHEMBL2821756 | 0.81 | GRM5 (0.41) | GRM5FFAR1ERN1NPC1HCRTR1 | |
| SCHEMBL5172806 | 0.78 | PPARD (0.45) | PPARDPPARGPPARAGRM5FFAR1 | |
| SCHEMBL6766733 | 0.76 | FFAR1 (0.49) | GRM5FFAR1ERN1 | |
| SCHEMBL2824805 | 0.76 | PPARD (0.44) | PPARDPPARGPPARA | |
| SCHEMBL2822191 | 0.76 | GRM5 (0.43) | PPARDPPARGPPARAGRM5FFAR1 | |
| SCHEMBL12590669 | 0.74 | PPARD (0.77) | PPARDPPARGPPARA | |
| SCHEMBL2827431 | 0.73 | PPARG (0.40) | PPARDPPARGPPARAGRM5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |