Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822197 | 0.86 | GRM5 (0.43) | GRM5PPARGPPARDPPARATP53 | |
| SCHEMBL2827431 | 0.84 | PPARG (0.40) | GRM5PPARGPPARDPPARAFFAR1 | |
| SCHEMBL2821756 | 0.83 | GRM5 (0.41) | GRM5TP53MAPTFFAR1 | |
| SCHEMBL2069995 | 0.79 | PPARD (0.60) | PPARGPPARDPPARA | |
| SCHEMBL2822346 | 0.77 | PPARD (0.41) | GRM5PPARDLMNAHPGD | |
| SCHEMBL2069381 | 0.77 | PPARA (0.46) | PPARGPPARDPPARAFFAR1 | |
| SCHEMBL2822183 | 0.76 | PPARD (0.44) | GRM5PPARGPPARDPPARAMAPT | |
| SCHEMBL2822103 | 0.76 | PPARD (0.47) | GRM5PPARGPPARDPPARAFFAR1 | |
| SCHEMBL2820978 | 0.72 | GRM5 (0.44) | GRM5 | |
| SCHEMBL2825490 | 0.72 | FFAR1 (0.34) | GRM5PPARGPPARDPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |