Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538429 | 0.86 | GSTP1 (0.52) | GSTP1HDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL7592278 | 0.86 | CYP1A2 (0.50) | GSTP1CYP1A2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL668420 | 0.82 | ALDH1A1 (0.44) | CYP1A2CYP1B1CYP1A1ALDH1A1HSD17B10 | |
| SCHEMBL3193310 | 0.82 | GSTP1 (0.64) | GSTP1HDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL28824090 | 0.82 | GSTP1 (0.43) | GSTP1HDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL25626307 | 0.82 | GSTP1 (0.43) | GSTP1HDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL3193631 | 0.80 | GSTP1 (0.61) | GSTP1HDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL28134614 | 0.79 | GSTP1 (0.45) | GSTP1HDAC4HDAC2HDAC8SLC6A2 | |
| SCHEMBL196008 | 0.77 | GSTP1 (0.53) | GSTP1HDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL30274189 | 0.76 | GSTP1 (0.57) | GSTP1HDAC4HDAC2HDAC8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129277-A | A kind of method for synthesizing 2,2 '-dinaphthyl ether | 上海博栋化学科技有限公司 | 2018-06-08 | — | — | CN | disclosed |