SCHEMBL28222983

SCHEMBL28222983

CCC(C)(C)c1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.57
ESR1 P03372 12/20 0.56
ESR2 Q92731 11/20 0.56
CYP3A4 P08684 2/20 0.50
KIF11 P52732 1/20 0.50
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
AR P10275 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR6 P50406 1/20 0.50
ESRRG P62508 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HSD17B10 Q99714 1/20 0.50
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49704 0.93 SHBG (0.64) SHBGESR1ESR2CYP3A4LMNA
Ammonia Solution, Strong SCHEMBL28084841 0.91 SHBG (0.61) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL9490738 0.91 SHBG (0.61) SHBGESR1ESR2CYP3A4LMNA
Potassium SCHEMBL29827429 0.91 SHBG (0.61) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL29827667 0.91 SHBG (0.61) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL2811934 0.91 SHBG (0.61) SHBGESR1ESR2CYP3A4LMNA
Hydrogen Sulfide SCHEMBL11598921 0.91 SHBG (0.61) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL5552840 0.89 NPC1 (0.52) SHBGESR1ESR2KIF11LMNA
SCHEMBL3292125 0.89 NPC1 (0.52) SHBGESR1ESR2KIF11LMNA
SCHEMBL9405142 0.87 SHBG (0.57) SHBGESR1ESR2CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105599169-B The manufacturing method of polyacetals particle 旭化成株式会社 2019-03-05 CN disclosed
CN-108069843-A The method for preparing cyclohexanone and derivative 国际香料和香精公司 2018-05-25 CN disclosed