SCHEMBL28223102

SCHEMBL28223102

CCCCCCNc1cc(C)nc2ccccc12

nearest known ligand 0.89

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.66
NCF1 P14598 2/20 0.64
NQO2 P16083 4/20 0.60
SLC2A1 P11166 1/20 0.58
NR4A2 P43354 1/20 0.58
ELANE P08246 2/20 0.53
OPRK1 P41145 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27895835 1.00 CYP2C19 (0.66) CYP2C19NCF1NQO2SLC2A1NR4A2
Iodide SCHEMBL6297962 0.99 CYP2C19 (0.64) CYP2C19NCF1NQO2SLC2A1NR4A2
SCHEMBL22390054 0.94 CYP2C19 (0.73) CYP2C19NCF1NQO2SLC2A1OPRK1
Quindecamine SCHEMBL2111177 0.94 CYP2C19 (0.73) CYP2C19NCF1NQO2SLC2A1OPRK1
SCHEMBL15923206 0.92 NCF1 (0.63) CYP2C19NCF1NQO2SLC2A1NR4A2
SCHEMBL11934982 0.87 CYP2C19 (0.64) CYP2C19NCF1NQO2SLC2A1OPRK1
SCHEMBL8685979 0.87 CYP2C19 (0.77) CYP2C19NCF1NQO2SLC2A1OPRK1
Quindecamine SCHEMBL190923 0.86 NQO2 (0.69) CYP2C19NCF1NQO2SLC2A1OPRK1
SCHEMBL14588165 0.86 NQO2 (0.65) CYP2C19NCF1NQO2SLC2A1OPRK1
SCHEMBL28506410 0.84 SLC2A1 (0.57) CYP2C19SLC2A1NR4A2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104981249-B Antimicrobe compound, their synthesis and its application 英国卫生部 2018-06-19 CN disclosed