Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28223129

CCCCCCCCCCCCc1cc2ccccc2c(N)c1C.O=C(O)C(F)(F)F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
USP2 O75604 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GLA P06280 1/20 0.45
CYP3A4 P08684 1/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TLR8 Q9NR97 6/20 0.42
S1PR1 P21453 4/20 0.39
S1PR4 O95977 3/20 0.39
S1PR5 Q9H228 2/20 0.39
LMNA P02545 1/20 0.39
TSHR P16473 1/20 0.39
FAAH O00519 1/20 0.38
OXER1 Q8TDS5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28222492 1.00 MAPT (0.45) MAPTKDM4EUSP2ALDH1A1GLA
Trifluoroacetic Acid SCHEMBL28223157 1.00 MAPT (0.45) MAPTKDM4EUSP2ALDH1A1GLA
Trifluoroacetic Acid SCHEMBL28223154 0.95 TLR8 (0.42) MAPTKDM4EUSP2ALDH1A1GLA
SCHEMBL28222385 0.88 TLR8 (0.52) MAPTKDM4EUSP2ALDH1A1GLA
SCHEMBL28222384 0.88 TLR8 (0.52) MAPTKDM4EUSP2ALDH1A1GLA
SCHEMBL28860556 0.88 TLR8 (0.52) MAPTKDM4EUSP2ALDH1A1GLA
SCHEMBL28222389 0.82 TLR8 (0.53) MAPTKDM4EUSP2ALDH1A1GLA
Trifluoroacetic Acid SCHEMBL28223133 0.79 MEN1 (0.38) MAPTKDM4EALDH1A1GLACYP3A4
SCHEMBL11690313 0.76 MAPT (0.53) MAPTKDM4EUSP2ALDH1A1GLA
Trifluoroacetic Acid SCHEMBL17260142 0.76 TLR8 (0.40) MAPTKDM4EUSP2ALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104981249-B Antimicrobe compound, their synthesis and its application 英国卫生部 2018-06-19 CN disclosed