Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222384 | 1.00 | TLR8 (0.52) | TLR8MAPTKDM4EUSP2ALDH1A1 | |
| SCHEMBL28860556 | 1.00 | TLR8 (0.52) | TLR8MAPTKDM4EUSP2ALDH1A1 | |
| SCHEMBL28222389 | 0.94 | TLR8 (0.53) | TLR8MAPTKDM4EUSP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28222492 | 0.88 | MAPT (0.45) | TLR8MAPTKDM4EUSP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28223129 | 0.88 | MAPT (0.45) | TLR8MAPTKDM4EUSP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28223157 | 0.88 | MAPT (0.45) | TLR8MAPTKDM4EUSP2ALDH1A1 | |
| SCHEMBL6578274 | 0.86 | TLR8 (0.54) | TLR8MAPTKDM4EUSP2ALDH1A1 | |
| SCHEMBL31265758 | 0.86 | MAPT (0.50) | TLR8MAPTKDM4EUSP2ALDH1A1 | |
| SCHEMBL31265756 | 0.86 | MAPT (0.50) | TLR8MAPTKDM4EUSP2ALDH1A1 | |
| SCHEMBL31265757 | 0.86 | MAPT (0.50) | TLR8MAPTKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981249-B | Antimicrobe compound, their synthesis and its application | 英国卫生部 | 2018-06-19 | — | — | CN | disclosed |