SCHEMBL28223554

SCHEMBL28223554

CCCCOC(=O)C(C=C(C)C(=O)O)C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
ATM Q13315 1/20 0.43
HCAR2 Q8TDS4 3/20 0.42
TSHR P16473 6/20 0.41
HPGD P15428 1/20 0.41
ESR1 P03372 3/20 0.36
MAPK1 P28482 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
NR1H2 P55055 1/20 0.36
RNASEL Q05823 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP3A4 P08684 1/20 0.35
NAAA Q02083 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6688614 0.73 ALDH1A1 (0.42) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL125263 0.72 ALDH1A1 (0.39) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL3019219 0.72 ALDH1A1 (0.39) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL4137626 0.72 ATM (0.39) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL11451495 0.72 ALDH1A1 (0.62) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL9127818 0.72 ALDH1A1 (0.62) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL8645656 0.72 ATM (0.59) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL8645658 0.72 ATM (0.59) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL598744 0.72 ATM (0.59) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL465991 0.71 ALDH1A1 (0.38) ALDH1A1ATMHCAR2TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108057028-A The Entogastric lingering peroral dosage form of the enteric coating of tablet form and its application and pharmaceutical composition 铁木医药有限公司 2018-05-22 CN disclosed