SCHEMBL28223752

SCHEMBL28223752

C[Si](C)(C)Oc1cccc(C=O)c1O[Si](C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.45
ERN1 O75460 2/20 0.44
TLR2 O60603 1/20 0.44
TLR1 Q15399 1/20 0.44
TLR6 Q9Y2C9 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
ALDH1A1 P00352 5/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 3/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1200637 0.82 ALDH1A1 (0.55) SRCERN1TLR2TLR1TLR6
SCHEMBL6906070 0.80 SRC (0.41) SRCERN1TLR2TLR1TLR6
SCHEMBL17318154 0.80 SMN1; SMN2 (0.33) CA1CA2ALDH1A1HPGDSMN1; SMN2
SCHEMBL2812943 0.77 TLR2 (0.32) SRCERN1TLR2TLR1TLR6
SCHEMBL2811728 0.76 ALDH1A1 (0.38) SRCERN1TLR2TLR1TLR6
SCHEMBL2871507 0.74 SRC (0.52) SRCERN1TLR2TLR1TLR6
SCHEMBL22245018 0.74 CA1 (0.49) SRCERN1TLR2TLR1TLR6
SCHEMBL8829590 0.72
SCHEMBL1753794 0.71 CA1 (0.50) SRCERN1TLR2TLR1TLR6
SCHEMBL1754368 0.71 SRC (0.54) SRCERN1TLR2TLR1TLR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105601782-B Hydroxyaryl functionalized polymers 株式会社普利司通 2019-06-18 CN disclosed
CN-107406632-B Rubber composition and tire 株式会社普利司通 2019-03-01 CN disclosed
CN-108350184-A Method for producing rubber composition and tire 株式会社普利司通 2018-07-31 CN disclosed
CN-108350231-A Rubber composition and tire 株式会社普利司通 2018-07-31 CN disclosed