Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.75 |
| ▸ | CA9 | Q16790 | 4/20 | 0.75 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37273 | 0.89 | ALDH1A1 (0.68) | CA1CA9GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL2998472 | 0.86 | CA1 (1.00) | CA1CA9GAAALDH1A1SMN1; SMN2 | |
| Pyridine SCHEMBL19329206 | 0.85 | ALDH1A1 (0.79) | CA1CA9GAAALPLALPI | |
| SCHEMBL28591667 | 0.84 | NPC1 (0.69) | CA1CA9GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL255625 | 0.83 | CA1 (0.65) | CA1CA9GAAALPLALPI | |
| SCHEMBL27960024 | 0.83 | ALDH1A1 (0.59) | CA1CA9GAAALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL872442 | 0.82 | CA1 (0.63) | CA1CA9GAAALPLALPI | |
| SCHEMBL2986200 | 0.80 | ALDH1A1 (0.83) | CA1CA9GAACYP2C9ALDH1A1 | |
| SCHEMBL6538536 | 0.79 | CTDSP1 (0.72) | CA1CA9GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL9131717 | 0.79 | ALDH1A1 (0.63) | CA1CA9GAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481769-B | A kind of benzo (c) acridine derivatives and its preparation method and application | 广西中医药大学 | 2018-07-10 | — | — | CN | disclosed |