Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28744029 | 1.00 | LOXL2 (0.56) | LOXL2MAPTCYP4A11MEN1KMT2A | |
| SCHEMBL9133770 | 0.84 | LOXL2 (0.62) | LOXL2MAPTCYP4A11MEN1KMT2A | |
| SCHEMBL8180714 | 0.83 | LOXL2 (0.56) | LOXL2MAPTCYP4A11MEN1KMT2A | |
| SCHEMBL1012811 | 0.83 | LOXL2 (0.61) | LOXL2MAPTCYP4A11MEN1KMT2A | |
| SCHEMBL8180716 | 0.83 | LOXL2 (0.56) | LOXL2MAPTCYP4A11MEN1KMT2A | |
| SCHEMBL10638128 | 0.83 | LOXL2 (0.56) | LOXL2MAPTCYP4A11MEN1KMT2A | |
| SCHEMBL223801 | 0.82 | LOXL2 (0.63) | LOXL2MAPTCYP4A11MEN1KMT2A | |
| SCHEMBL29158562 | 0.81 | LOXL2 (0.54) | LOXL2MAPTCYP4A11MEN1KMT2A | |
| SCHEMBL29158561 | 0.81 | LOXL2 (0.54) | LOXL2MAPTCYP4A11MEN1KMT2A | |
| SCHEMBL10587878 | 0.80 | LOXL2 (0.61) | LOXL2MAPTCYP4A11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101826-B | Indole-substituted alkylamine compound and application thereof | 华东理工大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-108101826-A | Indoles substituted alkylamine class compound and application thereof | 华东理工大学 | 2018-06-01 | — | — | CN | disclosed |