Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121972 | 0.92 | POLB (0.59) | MEN1KMT2APOLBCTDSP1ESR1 | |
| SCHEMBL6120888 | 0.88 | — | — | |
| SCHEMBL6121957 | 0.88 | CNR1 (0.55) | CNR1CNR2ALDH1A1HPGD | |
| SCHEMBL6122525 | 0.85 | KMT2A (0.56) | MEN1KMT2A | |
| SCHEMBL6122407 | 0.84 | KDM4E (0.52) | ALDH1A1 | |
| SCHEMBL28224702 | 0.82 | — | — | |
| SCHEMBL2057514 | 0.79 | CA9 (0.66) | MEN1KMT2APOLBESR1MAPT | |
| SCHEMBL13911246 | 0.79 | GAA (0.67) | MEN1KMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL6122269 | 0.78 | ALDH1A1 (0.54) | MEN1KMT2APOLBCTDSP1ESR1 | |
| SCHEMBL6121704 | 0.78 | CNR1 (0.73) | MAPTCNR1CNR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108164503-B | A kind of heteroaromatic and the disubstituted benzenesulfonamides of alkyl side chain and its preparing the application in anti-influenza A virus medicament | 武汉大学 | 2019-09-17 | — | — | CN | claimed |
| CN-108164503-A | A kind of heteroaromatic and the disubstituted benzenesulfonamides of alkyl side chain and its application in anti-influenza A virus medicament is prepared | 武汉大学 | 2018-06-15 | — | — | CN | claimed |