Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL6828046 | 0.89 | MEN1 (0.93) | MEN1KMT2ANR1H4MAPTLMNA | |
| Benzene SCHEMBL27988126 | 0.89 | MEN1 (1.00) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL935186 | 0.89 | MEN1 (1.00) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL28461515 | 0.88 | MEN1 (0.84) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL10665879 | 0.87 | MEN1 (0.59) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL9271893 | 0.85 | MAPT (0.78) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL9271895 | 0.85 | MAPT (0.78) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL11187652 | 0.85 | MEN1 (0.79) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL11187646 | 0.85 | MEN1 (0.79) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL28213002 | 0.84 | MEN1 (0.84) | MEN1KMT2ANR1H4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358831-A | A kind of polysubstituted carbazole derivates and preparation method thereof | 山东师范大学 | 2018-08-03 | — | — | CN | claimed |
| CN-108358831-B | Polysubstituted carbazole derivative and preparation method thereof | 山东师范大学 | 2020-09-29 | — | — | CN | disclosed |
| CN-108358831-A | A kind of polysubstituted carbazole derivates and preparation method thereof | 山东师范大学 | 2018-08-03 | — | — | CN | disclosed |