Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL27891800 | 0.84 | GAA (0.44) | MEN1KMT2ASMN1; SMN2LMNACYP3A4 | |
| Boric Acid SCHEMBL27983353 | 0.77 | TSHR (0.45) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL17101177 | 0.74 | GAA (0.44) | MEN1KMT2ASMN1; SMN2LMNACYP3A4 | |
| SCHEMBL557225 | 0.73 | MEN1 (0.38) | MEN1KMT2AHTTSMN1; SMN2GALR3 | |
| SCHEMBL19541483 | 0.71 | TSHR (0.49) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| SCHEMBL3325221 | 0.70 | MEN1 (0.35) | MEN1KMT2AHTTSMN1; SMN2GALR3 | |
| SCHEMBL28419069 | 0.70 | CYP19A1 (0.48) | MEN1KMT2AHTTSMN1; SMN2GALR3 | |
| Boric Acid SCHEMBL28182913 | 0.69 | ALDH1A1 (0.51) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL17101176 | 0.68 | GAA (0.41) | MEN1KMT2AHTTSMN1; SMN2LMNA | |
| Boric Acid SCHEMBL27984970 | 0.67 | NR4A1 (0.44) | MEN1KMT2ASMN1; SMN2CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683153-B | composition for treating hypertension and/or fibrosis | 维克图斯生物系统有限公司 | 2018-07-13 | — | — | CN | disclosed |