SCHEMBL28225656

SCHEMBL28225656

NCc1ccnc(-c2ccccc2)c1-c1ncccc1-c1cccnc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 5/20 0.43
DPP4 P27487 2/20 0.43
LOXL2 Q9Y4K0 1/20 0.42
CYP11B1 P15538 3/20 0.40
CYP11B2 P19099 3/20 0.40
PTGS2 P35354 2/20 0.40
CYP2A6 P11509 5/20 0.40
KCNN4 O15554 1/20 0.40
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
PTK2 Q05397 1/20 0.38
CCNK O75909 1/20 0.38
CDK12 Q9NYV4 1/20 0.38
CYP19A1 P11511 1/20 0.38
KCNH2 Q12809 1/20 0.38
CYP2E1 P05181 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2B6 P20813 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31038075 0.80 PTGS2 (0.56) KCNA5CYP11B1CYP11B2PTGS2CYP2A6
Benzylamine SCHEMBL28224987 0.78 CYP2A6 (0.53) KCNA5LOXL2CYP11B1CYP11B2PTGS2
Benzylamine SCHEMBL28225657 0.78 CYP2A6 (0.55) KCNA5LOXL2CYP11B1CYP11B2PTGS2
SCHEMBL28182272 0.77 PTGS2 (0.54) KCNA5CYP11B1CYP11B2PTGS2CYP2A6
SCHEMBL3288789 0.75 DPP4 (0.62) KCNA5DPP4LOXL2CYP11B1CYP11B2
Biphenyl SCHEMBL27783277 0.75 PTGS2 (0.59) KCNA5CYP11B1CYP11B2PTGS2CYP2A6
Benzene SCHEMBL9109284 0.75 PTGS2 (0.62) KCNA5CYP11B1CYP11B2PTGS2CYP2A6
Benzene SCHEMBL28446151 0.75 PTGS2 (0.62) KCNA5CYP11B1CYP11B2PTGS2CYP2A6
Benzene SCHEMBL15456827 0.75 PTGS2 (0.62) KCNA5CYP11B1CYP11B2PTGS2CYP2A6
SCHEMBL28860785 0.74 CYP2A6 (0.62) LOXL2CYP11B1CYP11B2PTGS2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108165261-A A kind of multicolor luminous gel based on terpyridine ligand and preparation method and application 南京邮电大学 2018-06-15 CN claimed
CN-108165261-A A kind of multicolor luminous gel based on terpyridine ligand and preparation method and application 南京邮电大学 2018-06-15 CN disclosed