Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PLD2 | O14939 | 1/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28225463 | 0.93 | NPC1 (0.43) | MAPTRXFP1EGFRPIK3CAPLD2 | |
| SCHEMBL28860919 | 0.87 | RXFP1 (0.40) | MAPTRXFP1EGFRPIK3CAPLD2 | |
| SCHEMBL28053768 | 0.83 | NPC1 (0.43) | MAPTEGFRPIK3CAIDO1KDR | |
| SCHEMBL28226242 | 0.82 | IDO1 (0.40) | MAPTEGFRPIK3CAIDO1PLD2 | |
| SCHEMBL28226164 | 0.79 | MAPT (0.42) | MAPTEGFRPIK3CAIDO1PLD2 | |
| SCHEMBL16402023 | 0.78 | MAPT (0.46) | MAPTRXFP1EGFRPIK3CAIDO1 | |
| SCHEMBL28053874 | 0.78 | EGFR (0.62) | MAPTEGFRPIK3CASMN1; SMN2NPC1 | |
| SCHEMBL28225440 | 0.78 | IDO1 (0.46) | MAPTEGFRPIK3CAIDO1KDR | |
| SCHEMBL28226165 | 0.75 | EGFR (0.40) | MAPTEGFRPIK3CAMAPK1SMN1; SMN2 | |
| SCHEMBL28225444 | 0.75 | SIRT2 (0.41) | MAPTEGFRPIK3CAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283443-B | Hete rocyclic derivatives and application thereof | 株式会社C&C新药研究所 | 2018-08-17 | — | — | CN | claimed |