Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094266 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL20186402 | 0.93 | DNM1 (0.40) | LMNAPOLBDNM1CA12CA1 | |
| SCHEMBL4233769 | 0.81 | — | — | |
| SCHEMBL15152152 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL10822892 | 0.79 | CA12 (0.50) | LMNAPOLBCA12CA1CA2 | |
| SCHEMBL8970424 | 0.78 | GABRR1 (0.41) | LMNAPOLBDNM1CA12CA1 | |
| SCHEMBL20186644 | 0.78 | DNM1 (0.43) | DNM1TAS1R3TAS1R1 | |
| SCHEMBL12583585 | 0.77 | — | — | |
| SCHEMBL19464383 | 0.77 | — | — | |
| SCHEMBL12583518 | 0.76 | DNM1 (0.48) | LMNAPOLBDNM1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108283644-A | To the instantaneous protection of normal cell during chemotherapy | G1治疗公司 | 2018-07-17 | — | — | CN | disclosed |