Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | BUB1 | O43683 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17250467 | 0.98 | NOTUM (0.58) | NOTUMHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL28226646 | 0.94 | ALK (0.54) | NOTUMHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29501296 | 0.87 | ALDH1A1 (0.67) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL3181560 | 0.87 | ALDH1A1 (0.67) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL23820568 | 0.85 | ALDH1A1 (0.64) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL2843753 | 0.85 | ALDH1A1 (0.71) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL29475332 | 0.85 | ALDH1A1 (0.71) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL29475330 | 0.85 | ALDH1A1 (0.71) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL25912532 | 0.85 | ALDH1A1 (0.64) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL28226596 | 0.85 | ALK (0.49) | NOTUMHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203405-A | Amine derivant of two fluorenes of benzo 9,9 '-spiral shell and preparation method thereof, application and device | 武汉尚赛光电科技有限公司 | 2018-06-26 | — | — | CN | disclosed |