Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1190703 | 0.93 | AR (0.49) | ARRXRARXRBRXRGPGR | |
| Tetrahydrofuran SCHEMBL28675347 | 0.82 | AR (0.41) | AR | |
| SCHEMBL189787 | 0.77 | AR (0.49) | ARPGR | |
| SCHEMBL4402110 | 0.77 | AR (0.51) | ARRXRARXRBRXRGPGR | |
| SCHEMBL1555041 | 0.74 | MAPK1 (0.47) | RXRARXRBRXRG | |
| SCHEMBL23877161 | 0.74 | AR (0.53) | ARRXRARXRBRXRGPGR | |
| SCHEMBL19500852 | 0.74 | CYP3A4 (0.39) | AR | |
| SCHEMBL4404032 | 0.73 | AR (0.51) | ARPGR | |
| SCHEMBL18856260 | 0.73 | AR (0.51) | ARPGR | |
| SCHEMBL58303 | 0.73 | MAPK1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108218784-A | A kind of preparation method of Nilutamide | 吴江信凯医药科技有限公司 | 2018-06-29 | — | — | CN | disclosed |