Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 18/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28227373 | 0.93 | AR (0.47) | ARPGRRXRARXRBRXRG | |
| Tetrahydrofuran SCHEMBL28675347 | 0.89 | AR (0.41) | AR | |
| SCHEMBL189787 | 0.83 | AR (0.49) | ARPGR | |
| SCHEMBL4402110 | 0.83 | AR (0.51) | ARPGRRXRARXRBRXRG | |
| SCHEMBL1555041 | 0.80 | MAPK1 (0.47) | RXRARXRBRXRG | |
| SCHEMBL19500852 | 0.80 | CYP3A4 (0.39) | AR | |
| SCHEMBL18856260 | 0.79 | AR (0.51) | ARPGR | |
| SCHEMBL4404032 | 0.79 | AR (0.51) | ARPGR | |
| SCHEMBL7177146 | 0.79 | MAPK1 (0.46) | — | |
| SCHEMBL10360634 | 0.78 | MAPK1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801064-A | Method for constructing phenylhydantoin by [3+2] cycloaddition reaction | 甘肃省化工研究院有限责任公司 | 2021-12-17 | — | — | CN | claimed |
| CN-112876391-A | Synthetic method of 4-isothiocyanato-2- (trifluoromethyl) benzonitrile | 山东铂源药业有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-115181043-B | Method for preparing 4-isothiocyanato-2- (trifluoromethyl) benzonitrile by continuous flow | 爱斯特（成都）生物制药股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023174062-A1 | METHOD FOR PREPARING NILUTAMIDE AND INTERMEDIATE THEREOF | 上海健康医学院 | 2023-09-21 | — | — | WO | disclosed |
| US-20230089368-A1 | POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES | ANAGENESIS BIOTECHNOLOGIES S.A.S. (FR) | 2023-03-23 | — | — | US | disclosed |
| CN-115181043-A | Method for preparing 4-isothiocyanato-2- (trifluoromethyl) benzonitrile by continuous flow | 爱斯特（成都）生物制药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-114605331-A | Preparation method of nilutamide and intermediate thereof | 上海健康医学院 | 2022-06-10 | — | — | CN | disclosed |
| EP-3999057-A1 | POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES | ANAGENESIS BIOTECHNOLOGIES SAS (FR) | 2022-05-25 | — | — | EP | disclosed |
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113801064-A | Method for constructing phenylhydantoin by [3+2] cycloaddition reaction | 甘肃省化工研究院有限责任公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-113801064-A | Method for constructing phenylhydantoin by [3+2] cycloaddition reaction | 甘肃省化工研究院有限责任公司 | 2021-12-17 | — | — | CN | disclosed |
| WO-2002000617-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR IDENTIFICATION, DESIGN AND USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |
| WO-2002000653-A2 | FUSED CYCLIC COMPOUNDS AS MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |
| EP-0916652-B1 | N-Aryl 2-hydroxy alkylamides | OREAL (FR) | 2001-10-31 | — | — | EP | disclosed |
| US-6156899-A | N-aryl-2-hydroxyalkylamido compositions for inducing/stimulating hair growth and/or retarding hair loss and/or for treating hyperseborrhea and/or acne | SOCIETE L'OREAL S.A. (FR) | 2000-12-05 | — | — | US | disclosed |
| US-6087509-A | DERIVATIVES OF TRIFLUOROBENZONITRILES | HOECHST MARION ROUSSEL (FR) | 2000-07-11 | — | — | US | disclosed |
| US-6057351-A | USEFUL FOR INDUCING AND/OR STIMULATING HAIR GROWTH AND/OR CONTROLLING HAIR LOSS AND/OR TREATING HYPERSEBORRHEA AND/OR ACNE | SOCIETE L'OREAL S.A. (FR) | 2000-05-02 | — | — | US | disclosed |
| EP-0915857-A1 | COMPOUNDS OF THE 3-ARYL 2,4 DIOXO OXAZOLIDINE FAMILY AND USE THEREOF IN COSMETICS AND PHARMACEUTICALS | L'OREAL (FR) | 1999-05-19 | — | — | EP | disclosed |
| EP-0916652-A1 | N-Aryl 2-hydroxy alkylamides | L'OREAL (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005654-A1 | COMPOUNDS OF THE 3-ARYL 2,4 DIOXO OXAZOLIDINE FAMILY AND USE THEREOF IN COSMETICS AND PHARMACEUTICALS | L'OREAL (FR) | 1998-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230089368-A1 | POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES | CKMT1A; CKMT1B, TNNC1, UBQLN2 | AR 928/4885PGR 1210/4885RXRA 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.