Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513 | 0.98 | TSHR (0.50) | TSHRGAAMGAMSIMGAM2 | |
| Acetic Acid SCHEMBL28073191 | 0.96 | TSHR (0.46) | TSHRGAAMGAMSIMGAM2 | |
| Acetone SCHEMBL28861611 | 0.96 | TSHR (0.48) | TSHRGAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL28225884 | 0.96 | TSHR (0.48) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL1616122 | 0.96 | TSHR (0.48) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL5702374 | 0.96 | TSHR (0.48) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL2221470 | 0.96 | TSHR (0.48) | TSHRGAAMGAMSIMGAM2 | |
| Acetic Acid SCHEMBL28081680 | 0.94 | TSHR (0.47) | TSHRGAAMGAMSIMGAM2 | |
| Isopropyl Alcohol SCHEMBL28650817 | 0.92 | TDP1 (0.47) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL7052633 | 0.90 | TSHR (0.44) | TSHRGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255747-B1 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | HOFFMANN LA ROCHE (CH) | 2006-10-04 | — | — | EP | claimed |
| US-6858749-B2 | Process for enantioselectively producing the (R)-delta-lactone | ROCHE COLORADO CORPORATION (US) | 2005-02-22 | — | — | US | claimed |
| US-20030171602-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | ROCHE COLORADO CORPORATION | 2003-09-11 | — | — | US | claimed |
| US-20030158423-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | ROCHE COLORADO CORPORATION (US) | 2003-08-21 | — | — | US | claimed |
| US-20030158422-A1 | Process for enantioselectively producing the (R)-delta-lactone | ROCHE COLORADO CORPORATION | 2003-08-21 | — | — | US | claimed |
| JP-2003521546-A | — | — | 2003-07-15 | — | — | JP | claimed |
| EP-1255747-A2 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | F. HOFFMANN-LA ROCHE AG (CH) | 2002-11-13 | — | — | EP | claimed |
| WO-2001057014-A2 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-09 | — | — | WO | claimed |
| CN-112368336-A | Resin composition and cured film thereof | 东丽株式会社 | 2021-02-12 | — | — | CN | disclosed |
| WO-2020045214-A1 | RESIN COMPOSITION AND CURED FILM OBTAINED THEREFROM | 東レ株式会社 | 2020-03-05 | — | — | WO | disclosed |
| EP-1942150-B1 | SILOXANE RESIN COMPOSITION AND METHOD FOR PRODUCING SAME | TORAY INDUSTRIES (JP) | 2018-08-22 | — | — | EP | disclosed |
| US-9625618-B2 | Optical member set and solid-state imaging element using the same | FUJIFILM CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| EP-2799913-B1 | OPTICAL MEMBER SET AND SOLID-STATE IMAGE SENSOR USING SAME | FUJIFILM CORP (JP) | 2017-02-01 | — | — | EP | disclosed |
| EP-2799912-A1 | OPTICAL MEMBER SET AND SOLID-STATE IMAGE PICKUP ELEMENT USING SAME | FUJI-FILM Corporation (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20030171602-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | ROCHE COLORADO CORPORATION | 2003-09-11 | — | — | US | disclosed |
| US-20030158422-A1 | Process for enantioselectively producing the (R)-delta-lactone | ROCHE COLORADO CORPORATION | 2003-08-21 | — | — | US | disclosed |
| US-20030158423-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | ROCHE COLORADO CORPORATION (US) | 2003-08-21 | — | — | US | disclosed |
| US-6545165-B1 | Cyclization | ROCHE COLORADO CORPORATION | 2003-04-08 | — | — | US | disclosed |
| EP-1255747-A2 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | F. HOFFMANN-LA ROCHE AG (CH) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001057014-A2 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158422-A1 | Process for enantioselectively producing the (R)-delta-lactone | DCXR, CYP51A1, RIOX2 | TSHR 1759/4885GAA 783/4885MGAM 398/4885 |
| US-20030171602-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | DHPS, HACL2, CYP8B1 | TSHR 2309/4885GAA 1134/4885MGAM 1870/4885 |
| US-20030158423-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | DHPS, HACL2, CYP8B1 | TSHR 2309/4885GAA 1134/4885MGAM 1870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.