Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27767987 | 0.84 | AAK1 (0.37) | PTGDR2RAB9ASMN1; SMN2KMT2ADGAT1 | |
| SCHEMBL27698022 | 0.83 | DGAT1 (0.44) | KMT2ADGAT1AAK1MEN1 | |
| SCHEMBL27890513 | 0.80 | HPGD (0.38) | PTGDR2LMNAKMT2ACYP3A4CYP1A2 | |
| SCHEMBL27681179 | 0.79 | MEN1 (0.38) | RAB9ASMN1; SMN2KMT2ACYP1A2MEN1 | |
| SCHEMBL27844219 | 0.77 | AAK1 (0.45) | RAB9ASMN1; SMN2NPC1AAK1 | |
| SCHEMBL2491151 | 0.75 | CYP3A4 (0.48) | LMNAKMT2ACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL27730118 | 0.74 | CYP3A4 (0.42) | RAB9ASMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL17593303 | 0.74 | NR1H2 (0.44) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL28784454 | 0.74 | SLC22A12 (0.40) | CYP3A4CYP1A2CYP2C9CYP2C19AAK1 | |
| SCHEMBL27541465 | 0.74 | PARP15 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377851-B | BET bromodomain inhibitors and therapeutic methods using these inhibitors | 密执安州立大学董事会 | 2018-07-20 | — | — | CN | disclosed |