Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638095 | 0.93 | KDM4E (0.81) | KDM4EMAPTALDH1A1DRD2DRD4 | |
| SCHEMBL3096217 | 0.93 | KDM4E (0.60) | KDM4EMAPTALDH1A1DRD2DRD4 | |
| SCHEMBL29906797 | 0.93 | KDM4E (0.60) | KDM4EMAPTALDH1A1DRD2DRD4 | |
| SCHEMBL29530477 | 0.93 | KDM4E (0.81) | KDM4EMAPTALDH1A1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL698487 | 0.92 | KDM4E (0.78) | KDM4EMAPTALDH1A1DRD2DRD4 | |
| SCHEMBL45202 | 0.83 | KDM4E (1.00) | KDM4EMAPTALDH1A1DRD2DRD4 | |
| SCHEMBL29365830 | 0.83 | KDM4E (0.76) | KDM4EMAPTALDH1A1ACHESRD5A2 | |
| SCHEMBL2730135 | 0.83 | KDM4E (0.76) | KDM4EMAPTALDH1A1ACHESRD5A2 | |
| SCHEMBL29673258 | 0.83 | KDM4E (1.00) | KDM4EMAPTALDH1A1DRD2DRD4 | |
| SCHEMBL4051485 | 0.81 | KDM4E (0.58) | KDM4EMAPTALDH1A1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276382-A | Cell cycle protein dependent kinase inhibitor and its application | 南京圣和药业股份有限公司 | 2018-07-13 | — | — | CN | disclosed |