Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638095 | 1.00 | KDM4E (0.81) | KDM4EMAPTDRD2DRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL698487 | 0.98 | KDM4E (0.78) | KDM4EMAPTDRD2DRD4ALDH1A1 | |
| SCHEMBL28229042 | 0.93 | KDM4E (0.71) | KDM4EMAPTDRD2DRD4ALDH1A1 | |
| SCHEMBL45202 | 0.89 | KDM4E (1.00) | KDM4EMAPTDRD2DRD4ALDH1A1 | |
| SCHEMBL29673258 | 0.89 | KDM4E (1.00) | KDM4EMAPTDRD2DRD4ALDH1A1 | |
| Imidazole SCHEMBL25325352 | 0.85 | KDM4E (0.61) | KDM4EMAPTDRD2DRD4ALDH1A1 | |
| SCHEMBL29906797 | 0.85 | KDM4E (0.60) | KDM4EMAPTDRD2DRD4ALDH1A1 | |
| SCHEMBL3096217 | 0.85 | KDM4E (0.60) | KDM4EMAPTDRD2DRD4ALDH1A1 | |
| SCHEMBL2610325 | 0.84 | MAPT (0.58) | KDM4EMAPTDRD2DRD4ALDH1A1 | |
| SCHEMBL4051485 | 0.84 | KDM4E (0.58) | KDM4EMAPTDRD2DRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374566-A1 | METHODS OF IDENTIFYING PROTEIN BINDING SITES ON RNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-23 | — | — | US | claimed |
| EP-4217364-A1 | METHODS OF IDENTIFYING PROTEIN BINDING SITES ON RNA | The Regents of the University of California (US) | 2023-08-02 | — | — | EP | claimed |
| WO-2022067036-A1 | METHODS OF IDENTIFYING PROTEIN BINDING SITES ON RNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-03-31 | — | — | WO | claimed |
| US-12365681-B2 | Dihydrobenzimidazolones for medical treatment | C4 THERAPEUTICS, INC. (US) | 2025-07-22 | — | — | US | disclosed |
| CN-115335043-B | PGDH inhibitors and methods of making and using the same | 迈欧伏特治疗公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240109889-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | US | disclosed |
| CN-112469699-B | Novel 3, 5-disubstituted pyridine and 3, 5-disubstituted pyridazine derivatives and medical application thereof | 田边三菱制药株式会社 | 2024-02-23 | — | — | CN | disclosed |
| US-20230374566-A1 | METHODS OF IDENTIFYING PROTEIN BINDING SITES ON RNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-23 | — | — | US | disclosed |
| US-11787802-B2 | Dihydrobenzimidazolones for medical treatment | C4 THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| EP-4217364-A1 | METHODS OF IDENTIFYING PROTEIN BINDING SITES ON RNA | The Regents of the University of California (US) | 2023-08-02 | — | — | EP | disclosed |
| US-20220363694-A1 | N-CYANO-7-AZANORBORNANE DERIVATIVES AND USES THEREOF | AMGEN INC. (US) | 2022-11-17 | — | — | US | disclosed |
| US-20220289738-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2022-09-15 | — | — | US | disclosed |
| WO-2022067036-A1 | METHODS OF IDENTIFYING PROTEIN BINDING SITES ON RNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365681-B2 | Dihydrobenzimidazolones for medical treatment | CRBN, CUL4A, ADRM1 | KDM4E 864/4885MAPT 2761/4885DRD2 4332/4885 |
| US-20240109889-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | CRBN, CUL4A, ADRM1 | KDM4E 864/4885MAPT 2761/4885DRD2 4332/4885 |
| US-20220289738-A1 | DIHYDROBENZIMIDAZOLONES FOR MEDICAL TREATMENT | CRBN, CUL4A, ADRM1 | KDM4E 864/4885MAPT 2761/4885DRD2 4332/4885 |
| US-11787802-B2 | Dihydrobenzimidazolones for medical treatment | CRBN, CUL4A, ADRM1 | KDM4E 864/4885MAPT 2761/4885DRD2 4332/4885 |
| US-20220363694-A1 | N-CYANO-7-AZANORBORNANE DERIVATIVES AND USES THEREOF | CYP3A7, CYP51A1, NT5C3B | KDM4E 586/4885MAPT 4708/4885DRD2 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.