Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.96 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.72 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27485345 | 1.00 | MEN1 (0.96) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| SCHEMBL2794662 | 0.98 | MEN1 (1.00) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| SCHEMBL219432 | 0.98 | MEN1 (1.00) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| Fluoride SCHEMBL27959930 | 0.96 | MEN1 (0.96) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| Hydrochloric Acid SCHEMBL7006476 | 0.96 | MEN1 (0.96) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| Hydrochloric Acid SCHEMBL11456225 | 0.96 | MEN1 (0.96) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| SCHEMBL8479321 | 0.90 | MEN1 (0.85) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| Propane SCHEMBL27542064 | 0.89 | MEN1 (0.82) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| Hydrochloric Acid SCHEMBL11455379 | 0.89 | MEN1 (0.82) | MEN1KMT2AOPRD1USP2CYP2C9 | |
| SCHEMBL27167001 | 0.89 | MEN1 (0.82) | MEN1KMT2AOPRD1USP2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955985-B | Etching solution, replenishment solution, and method for forming copper wiring | MEC股份有限公司 | 2018-07-20 | — | — | CN | disclosed |