SCHEMBL219432

SCHEMBL219432

c1ccc(C(c2ccccc2)N2CCNCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
OPRD1 P41143 13/20 0.74
USP2 O75604 2/20 0.68
CYP2C9 P11712 2/20 0.68
CYP2C19 P33261 1/20 0.68
CYP2D6 P10635 3/20 0.66
CYP19A1 P11511 1/20 0.66
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
OPRM1 P35372 2/20 0.59
CHRM2 P08172 1/20 0.59
CHRM4 P08173 1/20 0.59
CHRM5 P08912 1/20 0.59
ADRA2A P08913 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
CHRM1 P11229 1/20 0.59
CHRM3 P20309 1/20 0.59
DRD1 P21728 1/20 0.59
ADRA1D P25100 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2794662 1.00 MEN1 (1.00) MEN1KMT2AOPRD1USP2CYP2C9
SCHEMBL27485345 0.98 MEN1 (0.96) MEN1KMT2AOPRD1USP2CYP2C9
Hydrochloric Acid SCHEMBL7006476 0.98 MEN1 (0.96) MEN1KMT2AOPRD1USP2CYP2C9
Hydrochloric Acid SCHEMBL11456225 0.98 MEN1 (0.96) MEN1KMT2AOPRD1USP2CYP2C9
Piperazine SCHEMBL28229145 0.98 MEN1 (0.96) MEN1KMT2AOPRD1USP2CYP2C9
Fluoride SCHEMBL27959930 0.98 MEN1 (0.96) MEN1KMT2AOPRD1USP2CYP2C9
SCHEMBL8479321 0.92 MEN1 (0.85) MEN1KMT2AOPRD1USP2CYP2C9
Propane SCHEMBL27542064 0.91 MEN1 (0.82) MEN1KMT2AOPRD1USP2CYP2C9
Hydrochloric Acid SCHEMBL11455379 0.91 MEN1 (0.82) MEN1KMT2AOPRD1USP2CYP2C9
SCHEMBL27167001 0.91 MEN1 (0.82) MEN1KMT2AOPRD1USP2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1970 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12527755-B2 Formulations containing acetaminophen and sulfoalkyl ether cyclodextrin CYDEX PHARMACEUTICALS, INC. (US) 2026-01-20 US claimed
CN-120044159-A Polygonatum sibiricum medicinal material species identification method based on polygonatum sibiricum characteristic compound and application 河北北方学院 2025-05-27 CN claimed
CN-118371269-A Piperazine ligand modified gold-based catalyst and application thereof in hydrochlorination of acetylene 鄂尔多斯市瀚博科技有限公司 2024-07-23 CN claimed
CN-113754597-B Benzhydryl piperazine compound containing linear olefin and preparation method thereof 凯美克(上海)医药科技有限公司 2024-07-16 CN claimed
CN-117925335-A Semiconductor titanium nitride cleaning solution, and preparation method and application thereof 浙江奥首材料科技有限公司 2024-04-26 CN claimed
CN-116869983-A Formulations comprising acetaminophen and sulfoalkyl ether cyclodextrin 锡德克斯药物公司 2023-10-13 CN claimed
US-20230270750-A1 CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-08-31 US claimed
CN-116472267-A Butyrylcholinesterase reactivating agent 法兰西国由中央军队卫生服务局代表 2023-07-21 CN claimed
EP-4188919-A1 CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS Etat Français représenté par la Direction Centrale Du Service de Santé des Armées (FR) 2023-06-07 EP claimed
CN-115737648-A Application of benzhydrylpiperazine compounds in treating echinococcosis 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) 2023-03-07 CN claimed
EP-0189679-A1 Novel crystalline form of 1-benzhydryl-4-allylpiperazine dihydrochloride and method for the production thereof SO "PHARMACHIM" (BG) 1986-08-06 EP claimed
EP-0062827-B1 NOVEL BENZAMIDE DERIVATIVES KYOWA HAKKO KOGYO CO., LTD (JP) 1986-07-23 EP claimed
US-4504481-A ENZYME INHIBITORS IN LIVER TO REDUCE TOXIC EFFECT OF DRUGS RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1985-03-12 US claimed
EP-0006227-B1 ANTITHROMBOTIC PHARMACEUTICAL PREPARATION CONTAINING 2,2'-DITHIOBIS BENZAMIDE DERIVATIVES AND NEW 2,2'-DITHIOBIS BENZAMIDE DERIVATIVES KYOWA HAKKO KOGYO CO., LTD (JP) 1984-12-27 EP claimed
EP-0115203-A1 Benzhydrylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them Richter Gedeon Vegyészeti Gyár R.T. (HU) 1984-08-08 EP claimed
EP-0058146-B1 2-(4-(DIPHENYLMETHYL)-1-PIPERAZINYL)-ACETIC ACIDS AND THEIR AMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS U C B, S.A. (BE) 1984-06-27 EP claimed
US-4448776-A Method of using certain substituted aliphatic secondary amines or their salts for easing breathing BUCHER KARL (CH) 1984-05-15 US claimed
EP-0097340-A2 Piperazine derivatives, a process for preparing them and pharmaceutical compositions FERRER INTERNACIONAL, S.A. (ES) 1984-01-04 EP claimed
EP-0062827-A2 Novel benzamide derivatives KYOWA HAKKO KOGYO CO., LTD (JP) 1982-10-20 EP claimed
EP-0058146-A1 2-(4-(Diphenylmethyl)-1-piperazinyl)-acetic acids and their amides, process for their preparation and pharmaceutical compositions U C B, S.A. (BE) 1982-08-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270750-A1 CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS BCHE, ACHE, CHAT MEN1 3307/4885KMT2A 1473/4885OPRD1 887/4885
US-12527755-B2 Formulations containing acetaminophen and sulfoalkyl ether cyclodextrin TPMT, GSTP1, ALB MEN1 4265/4885KMT2A 4604/4885OPRD1 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.