Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL28229230

C=C(CO)C(=O)OC.C=CC(=O)OC

nearest known ligand 0.38

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
TSHR P16473 6/20 0.38
HCAR2 Q8TDS4 2/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 2/20 0.33
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26127707 0.85 ALDH1A1 (0.50) ALDH1A1TSHRTP53HSD17B10
SCHEMBL36299 0.85
Acrylic Acid Methyl Ester SCHEMBL27571924 0.84 HSD17B10 (0.45) ALDH1A1TSHRHCAR2KEAP1NFE2L2
Acrylic Acid Methyl Ester SCHEMBL17979227 0.84 TSHR (0.38) ALDH1A1TSHRHCAR2KEAP1NFE2L2
Acrylic Acid Methyl Ester SCHEMBL28083209 0.82 ALDH1A1 (0.37) ALDH1A1TSHRHCAR2KEAP1NFE2L2
Acrylic Acid Methyl Ester SCHEMBL27473540 0.79 TSHR (0.43) ALDH1A1TSHRHCAR2KEAP1NFE2L2
Acrylic Acid Methyl Ester SCHEMBL302020 0.78 TSHR (0.52) ALDH1A1TSHRHCAR2KEAP1NFE2L2
Acrylic Acid Methyl Ester SCHEMBL27662771 0.78 TSHR (0.52) ALDH1A1TSHRHCAR2KEAP1NFE2L2
Acrylic Acid Methyl Ester SCHEMBL28112669 0.78
Acrylic Acid Methyl Ester SCHEMBL6060989 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368335-A Polyurethane-based curable composition containing polymer microparticles and having excellent mechanical strength 株式会社钟化 2018-08-03 CN disclosed