Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440796 | 0.83 | ADRA2C (0.72) | ADRA2CHSD17B10HDAC1HDAC8HDAC6 | |
| SCHEMBL2232108 | 0.81 | HSD17B10 (0.60) | ADRA2CHSD17B10KDM4EHPGDTSHR | |
| Bromide SCHEMBL30496129 | 0.81 | ADRA2C (0.70) | ADRA2CHSD17B10HDAC1HDAC8HDAC6 | |
| Bromide SCHEMBL29049211 | 0.80 | HSD17B10 (0.58) | ADRA2CHSD17B10KDM4EHPGDTSHR | |
| Ammonia Solution, Strong SCHEMBL28850909 | 0.80 | HSD17B10 (0.58) | ADRA2CHSD17B10KDM4EHPGDTSHR | |
| Hydrochloric Acid SCHEMBL4373569 | 0.80 | HSD17B10 (0.58) | ADRA2CHSD17B10KDM4EHPGDTSHR | |
| Iodide SCHEMBL29049215 | 0.80 | HSD17B10 (0.58) | ADRA2CHSD17B10KDM4EHPGDTSHR | |
| Water SCHEMBL29049225 | 0.80 | HSD17B10 (0.58) | ADRA2CHSD17B10KDM4EHPGDTSHR | |
| SCHEMBL5608826 | 0.79 | HTT (0.53) | ADRA2CKDM4EHPGDTSHRHTT | |
| SCHEMBL12956811 | 0.79 | HTT (0.46) | ADRA2CHDAC1HDAC8HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859651-B | Thiazole derivative and its synthetic method and application | 华东师范大学 | 2018-06-22 | — | — | CN | disclosed |