Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950633 | 0.85 | EGLN1 (0.43) | EGLN1CYP1A2CYP2A6PDPK1DPP4 | |
| SCHEMBL9318876 | 0.82 | EGLN1 (0.47) | EGLN1EGFRCYP1A2CYP2A6PDPK1 | |
| SCHEMBL1658084 | 0.81 | EGLN1 (0.41) | EGLN1CYP1A2CYP2A6PDPK1DPP4 | |
| SCHEMBL214090 | 0.81 | LCK (0.56) | EGLN1CYP1A2CYP2A6LCKMAPT | |
| SCHEMBL29840564 | 0.81 | LCK (0.56) | EGLN1CYP1A2CYP2A6LCKMAPT | |
| SCHEMBL29746814 | 0.80 | EGLN1 (0.54) | EGLN1EGFRCYP1A2CYP2A6PDPK1 | |
| SCHEMBL155043 | 0.80 | EGLN1 (0.54) | EGLN1EGFRCYP1A2CYP2A6PDPK1 | |
| SCHEMBL29489052 | 0.80 | EGLN1 (0.54) | EGLN1EGFRCYP1A2CYP2A6PDPK1 | |
| Hydrochloric Acid SCHEMBL27800514 | 0.79 | LCK (0.55) | EGLN1CYP1A2CYP2A6LCKMAPT | |
| Water SCHEMBL1201320 | 0.78 | EGLN1 (0.53) | EGLN1EGFRCYP1A2CYP2A6PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341777-A | Compound of isobioquin group and its application | 四川科伦博泰生物医药股份有限公司 | 2018-07-31 | — | — | CN | disclosed |