Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GABRP | O00591 | 2/20 | 0.54 |
| ▸ | GABRD | O14764 | 2/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.54 |
| ▸ | GABRE | P78334 | 2/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29840564 | 1.00 | LCK (0.56) | LCKGABRA1GABRG2GABRB3GABRA5 | |
| Hydrochloric Acid SCHEMBL27800514 | 0.98 | LCK (0.55) | LCKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29840495 | 0.88 | EGLN1 (0.46) | LCKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29840579 | 0.88 | EGLN1 (0.46) | LCKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9318876 | 0.84 | EGLN1 (0.47) | LCKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL1202164 | 0.83 | LCK (0.55) | LCKKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL27950633 | 0.83 | EGLN1 (0.43) | LCKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL28674760 | 0.82 | ABL1 (0.55) | LCKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL6583631 | 0.82 | ALDH1A1 (0.45) | LCKGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL3834448 | 0.81 | KDM4E (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294833-B | Isoquinolin -3- formyl-RI-OBzl are prepared, nanostructure, activity and application | 首都医科大学 | 2018-09-07 | — | — | CN | claimed |
| CN-108017583-A | A kind of preparation method for winning U.S. | 徐州万邦金桥制药有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-104211767-B | The formamido group acyl oligopeptides of isoquinolin 3, it is prepared, nanostructured, antitumor activity and application | 首都医科大学 | 2017-08-18 | — | — | CN | claimed |
| CN-103450338-B | The Thymopentin that heterocyclic carboxylic acid is modified, it prepares, antitumor action and application | 首都医科大学 | 2016-08-24 | — | — | CN | claimed |
| CN-103435546-B | Process for preparing isoquinoline compounds | 菲布罗根有限公司 | 2016-08-10 | — | — | CN | claimed |
| CN-102584699-B | Process for preparing 3-acetylisoquinoline and derivatives thereof | NANO & ADVANCED MATERIALS INST LTD | 2014-08-20 | — | — | CN | claimed |
| CN-103435546-A | Process for preparing isoquinoline compounds | FIBROGEN INC | 2013-12-11 | — | — | CN | claimed |
| CN-102584699-A | Process for preparing 3-acetylisoquinoline and derivatives thereof | NANO & ADVANCED MATERIALS INST LTD | 2012-07-18 | — | — | CN | claimed |
| US-6306203-B1 | FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING | XEROX CORPORATION | 2001-10-23 | — | — | US | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| US-20260034094-A1 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | KOJIN THERAPEUTICS INC (US) | 2026-02-05 | — | — | US | disclosed |
| EP-4565228-A2 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | Kojin Therapeutics, Inc. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024217500-A1 | ISOQUINOLINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2024-10-24 | — | — | WO | disclosed |
| CN-114423749-B | Isoquinoline derivatives and their use for the treatment of parasitic infections | 拜耳动物保健有限责任公司 | 2024-10-01 | — | — | CN | disclosed |
| US-5631264-A | NEUROLOGICAL DISORDERS | SANOFI WINTHROP, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5554620-A | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof | STERLING WINTHROP INC. (US) | 1996-09-10 | — | — | US | disclosed |
| CN-1107145-A | Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |
| EP-0656359-A1 | Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts and compositionsand methods of use thereof | STERLING WINTHROP INC. (US) | 1995-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034094-A1 | COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS | AIFM2, GPX4, HMOX1 | LCK 2684/4885GABRA1 3371/4885GABRG2 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.