Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | DCUN1D2 | Q6PH85 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397443 | 0.99 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL31006315 | 0.99 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL2823570 | 0.97 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL2822952 | 0.97 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL27787520 | 0.84 | ALDH1A1 (0.32) | ALDH1A1DCUN1D2DCUN1D1PELI1 | |
| Lithium SCHEMBL1562536 | 0.84 | DRD1 (0.41) | ALDH1A1CYP2A6XDHDCUN1D2DCUN1D1 | |
| SCHEMBL1561472 | 0.82 | DRD1 (0.42) | ALDH1A1KCNJ1CYP2A6XDHDCUN1D2 | |
| SCHEMBL1561381 | 0.81 | DRD1 (0.41) | ALDH1A1CYP2A6XDHDCUN1D2DCUN1D1 | |
| Potassium SCHEMBL1561386 | 0.81 | DRD1 (0.41) | ALDH1A1CYP2A6XDHDCUN1D2DCUN1D1 | |
| SCHEMBL1561389 | 0.81 | DRD1 (0.41) | ALDH1A1CYP2A6XDHDCUN1D2DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728024-B2 | Metal salts of 2′-(1H-Tetrazol-5yl)-1.1′-biphenyl-4-carboxaldehyde | NOVARTIS AG (CH) | 2010-06-01 | — | — | US | claimed |
| CN-101468972-A | Metal salt of 2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-carbaldehyde | NOVARTIS AG (CH) | 2009-07-01 | — | — | CN | claimed |
| CN-101208313-A | Metal salts of 2 '- (1H-tetrazol-5-yl) -1, 1' -biphenyl-4-carbaldehyde | NOVARTIS AG (CH) | 2008-06-25 | — | — | CN | claimed |
| CN-101468972-A | Metal salt of 2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-carbaldehyde | NOVARTIS AG (CH) | 2009-07-01 | — | — | CN | disclosed |
| CN-101208313-A | Metal salts of 2 '- (1H-tetrazol-5-yl) -1, 1' -biphenyl-4-carbaldehyde | NOVARTIS AG (CH) | 2008-06-25 | — | — | CN | disclosed |