Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.36 |
| ▸ | CDK2 | P24941 | 5/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | OGA | O60502 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230019 | 0.85 | HRH3 (0.42) | CCNE1CDK2GSK3BOGASMN1; SMN2 | |
| SCHEMBL28304471 | 0.85 | CCNE1 (0.39) | CCNE1CDK2GSK3B | |
| SCHEMBL28230861 | 0.84 | CCNE1 (0.39) | CCNE1CDK2GSK3BOGASMN1; SMN2 | |
| SCHEMBL18641456 | 0.84 | MEN1 (0.33) | OGASMN1; SMN2HTTBCHEALDH1A1 | |
| SCHEMBL18641364 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTALDH1A1MEN1GAA | |
| SCHEMBL24823222 | 0.69 | PDPK1 (0.42) | — | |
| SCHEMBL28874646 | 0.68 | CCNE1 (0.42) | CCNE1CDK2GSK3BHRH3 | |
| SCHEMBL27756963 | 0.68 | BCHE (0.69) | BCHEALDH1A1MEN1KMT2AACKR3 | |
| SCHEMBL18641566 | 0.68 | ALDH1A1 (0.37) | OGASMN1; SMN2HTTALDH1A1MEN1 | |
| SCHEMBL19975166 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108347943-A | HEPATITIS B CORE PROTEIN MODULATORS | 组装生物科学股份有限公司 | 2018-07-31 | — | — | CN | disclosed |