Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.80 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754254 | 0.93 | HTR7 (0.71) | HTR7DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL30108234 | 0.91 | HTR7 (0.69) | HTR7DRD2DRD4DRD3HRH3 | |
| SCHEMBL15826880 | 0.91 | HTR7 (0.69) | HTR7DRD2DRD4DRD3HRH3 | |
| SCHEMBL29764254 | 0.89 | HTR7 (1.00) | HTR7DRD2DRD4DRD3 | |
| SCHEMBL15938148 | 0.89 | HTR7 (1.00) | HTR7DRD2DRD4DRD3 | |
| SCHEMBL15938089 | 0.88 | HTR7 (0.78) | HTR7DRD2DRD4DRD3 | |
| SCHEMBL30616744 | 0.87 | HTR7 (0.64) | HTR7DRD2DRD4DRD3DPP4 | |
| SCHEMBL1111683 | 0.87 | HTR7 (0.64) | HTR7DRD2DRD4DRD3DPP4 | |
| SCHEMBL29415418 | 0.87 | HTR7 (0.69) | HTR7 | |
| SCHEMBL2472212 | 0.87 | HTR7 (0.64) | HTR7DRD2DRD4DRD3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276356-A | 3,5- disubstituted thiazole alkane -2- thioketone preparation methods | 苏州大学 | 2018-07-13 | — | — | CN | disclosed |