⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28091576 | 0.67 | — | — | |
| SCHEMBL12247762 | 0.67 | — | — | |
| SCHEMBL13789969 | 0.67 | — | — | |
| SCHEMBL27346997 | 0.67 | — | — | |
| SCHEMBL28764344 | 0.67 | SIGMAR1 (0.32) | — | |
| SCHEMBL12719881 | 0.61 | — | — | |
| SCHEMBL13092425 | 0.61 | — | — | |
| SCHEMBL20342114 | 0.61 | — | — | |
| SCHEMBL21510526 | 0.61 | — | — | |
| SCHEMBL1993148 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290860-B | Iminotetrahydropyrimidinone derivatives as PLASMEPSIN V inhibitors | UCB生物制药有限责任公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-108290860-A | Imino group tetrahydropyrimidine ketone derivatives as PLASMEPSIN V inhibitor | UCB生物制药私人有限公司 | 2018-07-17 | — | — | CN | disclosed |