Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823206 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDPOLBMAOA | |
| Trifluoroacetic Acid SCHEMBL1238716 | 0.95 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDPOLBMAOA | |
| Trifluoroacetic Acid SCHEMBL1238713 | 0.95 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDPOLBMAOA | |
| SCHEMBL14870573 | 0.93 | KDM4E (0.55) | ALDH1A1KDM4EHPGDPOLBMAOA | |
| SCHEMBL14870574 | 0.89 | KDM4E (0.50) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL1239255 | 0.89 | KDM4E (0.50) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL1239258 | 0.89 | KDM4E (0.50) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL12712438 | 0.86 | KDM4E (0.48) | ALDH1A1KDM4EHPGDPOLBMAOA | |
| SCHEMBL14870580 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL1239838 | 0.84 | KDM4E (0.48) | ALDH1A1KDM4EHPGDPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261218-A2 | Process for preparing phenyl-, pyridinyl- or pyrimidinyl-substituted imidazoles | Eisai R&D Management Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |