Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | GMNN | O75496 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22485402 | 1.00 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL27586586 | 0.88 | LMNA (0.72) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| Acetylcarnitine SCHEMBL3259109 | 0.86 | LMNA (0.96) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| Acetylcarnitine SCHEMBL13323920 | 0.86 | LMNA (0.96) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| Acetylcarnitine SCHEMBL7079427 | 0.86 | LMNA (0.96) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| Acetylcarnitine SCHEMBL2515409 | 0.84 | LMNA (0.93) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL22056499 | 0.84 | LMNA (0.68) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL22057130 | 0.84 | LMNA (0.68) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| Acetylcarnitine SCHEMBL20721036 | 0.84 | LMNA (0.93) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL22485363 | 0.84 | LMNA (0.68) | LMNASMN1; SMN2CYP1A2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109946390-A | A kind of combination of pulmonary cancer diagnosis marker and application | 上海生物信息技术研究中心 | 2019-06-28 | — | — | CN | claimed |
| CN-108627647-A | A kind of detection of posttranslational modification proteomics and quantitative approach | 四川大学 | 2018-10-09 | — | — | CN | claimed |
| CN-110505873-A | Intranasal epinephrine formulations and methods of treating disease | ARS PHARMACEUTICALS INC | 2019-11-26 | — | — | CN | disclosed |
| CN-110139651-A | For treating the excessive composition of opioid and method | 欧邦特制药公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-109946390-A | A kind of combination of pulmonary cancer diagnosis marker and application | 上海生物信息技术研究中心 | 2019-06-28 | — | — | CN | disclosed |
| CN-109946390-A | A kind of combination of pulmonary cancer diagnosis marker and application | 上海生物信息技术研究中心 | 2019-06-28 | — | — | CN | disclosed |
| CN-109870535-A | A kind of extensive qualitative method of fatty acyl carnitine based on mixed biologic sample | 中国科学院大连化学物理研究所 | 2019-06-11 | — | — | CN | disclosed |
| CN-108627647-A | A kind of detection of posttranslational modification proteomics and quantitative approach | 四川大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-108369612-A | Automated sample quality assessment | 梅塔博隆股份有限公司 | 2018-08-03 | — | — | CN | disclosed |