Butyric Acid

Butyric Acid

SCHEMBL28233191

CCCC(=O)O.NC(=O)C1CNCCN1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
KMT2A Q03164 2/20 0.33
SLC6A1 P30531 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRB2 P47870 2/20 0.33
SLC6A12 P48065 2/20 0.33
SLC6A11 P48066 2/20 0.33
SLC6A13 Q9NSD5 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
CYP2D6 P10635 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28060482 0.83 KDM4E (0.38) KMT2ASLC6A1GABRA5GABRB2SLC6A12
SCHEMBL5328 0.82
SCHEMBL869800 0.82
SCHEMBL5909288 0.82
Piperazine SCHEMBL28120340 0.80 KDM4E (0.42) KMT2ASLC6A1GABRA5GABRB2SLC6A11
Hydrochloric Acid SCHEMBL27837986 0.80 KDM4E (0.42) KMT2ASLC6A1SLC6A11SLC6A13KDM4E
Hydrochloric Acid SCHEMBL27871150 0.80 KDM4E (0.42) KMT2ASLC6A1SLC6A11SLC6A13KDM4E
Butyric Acid SCHEMBL28233163 0.80 FFAR3 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL28233195 0.80 FFAR3 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL28233171 0.80 FFAR3 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108419435-A Compound and epigenetics for treating cancer 新加坡科技研究局 2018-08-17 CN disclosed