Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21689281 | 0.86 | HDAC1 (0.68) | HDAC1HDAC8HDAC6ALDH1A1TP53 | |
| SCHEMBL17487352 | 0.85 | HDAC1 (0.67) | HDAC1HDAC8HDAC6ALDH1A1MAPT | |
| SCHEMBL27237310 | 0.85 | HDAC1 (0.55) | HDAC1HDAC8HDAC6ALDH1A1SCN10A | |
| SCHEMBL21639144 | 0.85 | HDAC1 (0.68) | HDAC1HDAC8HDAC6ALDH1A1TP53 | |
| SCHEMBL2221957 | 0.85 | HDAC1 (0.67) | HDAC1HDAC8HDAC6ALDH1A1MAPT | |
| SCHEMBL25002914 | 0.85 | HDAC1 (0.74) | HDAC1HDAC8HDAC6ALDH1A1MAPT | |
| SCHEMBL6386434 | 0.84 | HDAC1 (0.65) | HDAC1HDAC8HDAC6ALDH1A1PDE4B | |
| SCHEMBL6392931 | 0.84 | HDAC1 (0.51) | HDAC1HDAC8HDAC6ALDH1A1SCN10A | |
| SCHEMBL24339961 | 0.84 | ELANE (0.53) | HDAC1HDAC8HDAC6ALDH1A1MAPT | |
| SCHEMBL3558409 | 0.83 | HDAC1 (0.52) | HDAC1HDAC8HDAC6ALDH1A1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604326-A1 | PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND | FUJIFILM Corporation (JP) | 2020-02-05 | — | — | EP | disclosed |
| EP-2226322-B1 | IMIDAZOLE CARBONYL COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-01-21 | — | — | EP | disclosed |
| US-8927588-B2 | Imidazole carbonyl compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-01-06 | — | — | US | disclosed |
| US-20140073622-A1 | IMIDAZOLE CARBONYL COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-03-13 | — | — | US | disclosed |
| US-8536197-B2 | Imidazole carbonyl compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-09-17 | — | — | US | disclosed |
| US-20100311966-A1 | IMIDAZOLE CARBONYL COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-2226322-A1 | IMIDAZOLE CARBONYL COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2010-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311966-A1 | IMIDAZOLE CARBONYL COMPOUND | TOP1, TOP2B, TOP2A | HDAC1 218/4885HDAC8 174/4885HDAC6 427/4885 |
| US-20140073622-A1 | IMIDAZOLE CARBONYL COMPOUND | TOP1, TOP2B, TOP2A | HDAC1 41/4885HDAC8 320/4885HDAC6 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.