Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 11/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14708214 | 0.85 | CACNA1H (0.52) | CACNA1HDRD2JAK2JAK1EPHX1 | |
| SCHEMBL1428134 | 0.84 | CACNA1H (0.51) | CACNA1HDRD2JAK2JAK1EPHX1 | |
| SCHEMBL16480069 | 0.82 | CACNA1H (0.54) | CACNA1HDRD2JAK2JAK1EPHX1 | |
| SCHEMBL16095384 | 0.82 | CACNA1H (0.49) | CACNA1HDRD2JAK2JAK1EPHX1 | |
| SCHEMBL31301242 | 0.81 | DRD2 (0.63) | CACNA1HDRD2EPHX1SIGMAR1TDP1 | |
| SCHEMBL22470192 | 0.81 | DRD2 (0.52) | CACNA1HDRD2JAK2JAK1EPHX1 | |
| SCHEMBL14614740 | 0.81 | CACNA1H (0.53) | CACNA1HDRD2JAK2JAK1EPHX1 | |
| SCHEMBL24811481 | 0.80 | CACNA1H (0.52) | CACNA1HDRD2JAK2JAK1EPHX1 | |
| SCHEMBL24951961 | 0.80 | DRD2 (0.53) | CACNA1HDRD2JAK2JAK1EPHX1 | |
| SCHEMBL18687462 | 0.80 | CACNA1H (0.52) | CACNA1HDRD2JAK2JAK1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368071-A | Compounds having HIV maturation inhibitory activity | 葛兰素史克知识产权第二有限公司 | 2018-08-03 | — | — | CN | disclosed |