Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397138 | 0.87 | ALDH1A1 (0.59) | TSHRKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL28400693 | 0.84 | HSD17B10 (0.55) | TSHRKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL28406350 | 0.82 | ALDH1A1 (0.62) | TSHRKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL28399007 | 0.82 | TSHR (0.53) | TSHRKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL28956561 | 0.82 | HPGD (0.55) | TSHRHSD17B10ALDH1A1CYP1A2GLRA1 | |
| SCHEMBL28406235 | 0.82 | TSHR (0.56) | TSHRKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL28406328 | 0.81 | ALDH1A1 (0.53) | TSHRKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL28406248 | 0.81 | PARP1 (0.59) | TSHRGAAHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL28889060 | 0.81 | CCNT1 (0.53) | TSHRKMT2AMEN1GAAHSD17B10 | |
| SCHEMBL28406333 | 0.81 | GAA (0.58) | TSHRGAAALDH1A1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440389-A | 3,4,5-trihydroxy benzoic acid derivative and the preparation method and application thereof | 山东大学 | 2018-08-24 | — | — | CN | disclosed |