Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 17/20 | 0.44 |
| ▸ | HSD11B2 | P80365 | 12/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829684 | 0.84 | HSD11B1 (0.51) | HSD11B1HSD11B2 | |
| SCHEMBL2826237 | 0.83 | HSD11B1 (0.50) | HSD11B1HSD11B2 | |
| SCHEMBL2826810 | 0.83 | HSD11B1 (0.63) | HSD11B1HSD11B2 | |
| SCHEMBL2827032 | 0.81 | HSD11B1 (0.49) | HSD11B1HSD11B2 | |
| SCHEMBL2826298 | 0.81 | HSD11B1 (0.53) | HSD11B1HSD11B2 | |
| SCHEMBL2826300 | 0.81 | HSD11B1 (0.53) | HSD11B1HSD11B2 | |
| SCHEMBL2826302 | 0.81 | HSD11B1 (0.45) | HSD11B1HSD11B2SCN9A | |
| SCHEMBL2823874 | 0.79 | HSD11B1 (0.61) | HSD11B1HSD11B2 | |
| SCHEMBL2827460 | 0.79 | HSD11B1 (0.49) | HSD11B1HSD11B2 | |
| SCHEMBL2824659 | 0.79 | HSD11B1 (0.48) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | claimed |