Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819889 | 0.91 | MAPT (0.63) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL17002040 | 0.89 | MAPT (0.67) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL17002039 | 0.89 | MAPT (0.67) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL8994589 | 0.89 | MAPT (0.67) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL13267850 | 0.89 | MAPT (0.67) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL13267746 | 0.89 | MAPT (0.67) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL17002036 | 0.89 | MAPT (0.67) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL5026357 | 0.89 | MAPT (0.67) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| Butylbenzyl SCHEMBL27457856 | 0.89 | ALDH1A1 (0.58) | HPGDMAPTRXFP1HDAC3MAPK1 | |
| SCHEMBL3642535 | 0.89 | HDAC1 (0.64) | HPGDMAPTRXFP1HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |