Ethylene Glycol

Ethylene Glycol

SCHEMBL28237462

O=C(O)c1ccc(C(=O)OC(=O)c2ccc(C(=O)O)o2)cc1.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.48
ALDH1A1 P00352 2/20 0.46
TDP1 Q9NUW8 1/20 0.43
RXRA P19793 2/20 0.40
RXRB P28702 2/20 0.40
KMT2A Q03164 3/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
CYP4A11 Q02928 3/20 0.38
SRD5A2 P31213 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 1/20 0.38
CYP4F2 P78329 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
RXRG P48443 1/20 0.37
NR4A2 P43354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28499699 0.86 ALDH1A1 (0.43) POLBALDH1A1TDP1KMT2ATSHR
Terephthalic Acid SCHEMBL28439546 0.86 TDP1 (0.55) POLBALDH1A1TDP1KMT2ATP53
SCHEMBL7870939 0.82 TDP1 (0.48) POLBALDH1A1TDP1KMT2ASMN1; SMN2
Terephthalic Acid SCHEMBL18320901 0.78 TSHR (0.63) POLBALDH1A1TDP1KMT2ATP53
Ethylene Glycol SCHEMBL20377334 0.78 TDP1 (0.64) POLBALDH1A1TDP1KMT2AHPGD
Terephthalic Acid SCHEMBL28456229 0.78 TDP1 (0.50) POLBALDH1A1TDP1KMT2ATP53
Terephthalic Acid SCHEMBL28456298 0.78 TDP1 (0.50) POLBALDH1A1TDP1KMT2ATP53
SCHEMBL1269049 0.76 TSHR (0.67) ALDH1A1TP53TSHRSRD5A2SMN1; SMN2
SCHEMBL15129970 0.76 TSHR (0.67) ALDH1A1TP53TSHRSRD5A2SMN1; SMN2
SCHEMBL110030 0.76 TSHR (0.67) ALDH1A1TP53TSHRSRD5A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108484959-A 2,5- furandicarboxylic acid base copolyesters expanded materials and preparation method thereof 中国科学院宁波材料技术与工程研究所 2018-09-04 CN disclosed